Abstract: We investigate the feasibility of deriving surrogate ordinary differential equations (ODEs) from individual-based models (IBMs) simulated in the PhysiCell platform. As a preliminary ...

Five years ago, scientists watched in wonder as synthetic bacteria grew and split into daughter cells. The bacteria’s extremely stripped-down genome still supported its entire life cycle. It was a ...

The team simulated a living cell at nanoscale resolution and recapitulated how every molecule within that cell behaved over the course of a full cell cycle. The work took many years: vast computer ...

A simulated cell in the early stages of division. Left half shows cytoplasm (blue cubes), mRNA degradation machinery molecules (pink), and sugar transporters (brown). Right half adds the membrane ...

The researchers, led by chemistry professor Zan Luthey-Schulten at the University of Illinois Urbana-Champaign, present their findings in the journal Cell. In two videos, researchers describe the work ...

(Nanowerk News) By simulating the life cycle of a minimal bacterial cell — from DNA replication to protein translation to metabolism and cell division — scientists have opened a new frontier of ...

Following retinal injury, zebrafish Müller glia reenter the cell cycle and generate replacement cells; this potentially valuable study proposes that injury induces a cxcl18b+ transitional state in ...

Cell proliferation is a highly orchestrated process essential for growth, tissue repair, and maintaining homeostasis in multicellular organisms. During the cell cycle, cell division is regulated by ...

Life’s fundamental structure is the cell, and so the main things that a cell does — processing biomolecules, growing, replicating its genetic material and producing a new body — are considered ...